BIOCHEMICAL STUDIES OF RATS AFTER BONE IMPLANTATIONS OF MATERIALS ON THE BASE OF TTCP/ DCPA, TARTARIC OR ASCORBIC ACIDS

Authors

  • M. Gabrashanska Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences
  • S. Tepavitcharova Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences
  • R. Ilieva Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences
  • M. Alexandrov Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences
  • V. Nanev Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences
  • N. Tsocheva-Gaytandzhieva Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences
  • I. Vladov Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences
  • P. Dimitrov Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences

Keywords:

cements, bone markers, oxidative stress

Abstract

The study aimed to evaluate hematological levels of markers of bone turnover in rats with calvarial defects filled with modified calcium phosphates cements. Cements were synthesized basing on TTCP/DCPA, carboxylic acids, xanthan gum and glycerin. Total and bone alkaline phosphates, osteocalcin, and their relation with oxidative stress (malondialdehyde) were studied. No differences in the markers levels were observed between the groups with implants. The level of free radicals was significantly increased in all groups. The obtained data might be useful in future experiments with new bone implants.

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Published

2017-06-20

How to Cite

Gabrashanska, M., Tepavitcharova, S., Ilieva, R., Alexandrov, M., Nanev, V., Tsocheva-Gaytandzhieva, N., … Dimitrov, P. (2017). BIOCHEMICAL STUDIES OF RATS AFTER BONE IMPLANTATIONS OF MATERIALS ON THE BASE OF TTCP/ DCPA, TARTARIC OR ASCORBIC ACIDS. TRADITION AND MODERNITY IN VETERINARY MEDICINE, 2(1), 9–12. Retrieved from https://www.scij-tmvm.com/index.php/pub/article/view/28