STUDY OF THE INTERFERON-INDUCING ACTIVITY OF A VACCINE STRAIN OF BOVINE RESPIRATORY SYNCYTIAL VIRUS

Abstract

Bovine respiratory syncytial virus (BRSV) is major viral component of bovine respiratory disease (BRD). BRD is a major cause of morbidity and mortality in all classes of cattle but particularly young beef and dairy calves. The actuality of this infection is preserved regardless of the change in the technology of cattle breeding in our country at the present stage and therefore the study of immune factors is essential. Along with studying different immune factors, we proved that the vaccine strain "An-87"of the BRSV has a well-defined interferon-inducing activity. The highest values of interferon are found in the secretions of the respiratory tract in tracheally applied antigen on the 3d day.